脫氧核糖核酸酶2抗體，DNase II應(yīng)用方法

發(fā)布時(shí)間：2022-05-16 閱讀：545次

英文名稱 DNase II

中文名稱脫氧核糖核酸酶2抗體

別名 Acid DNase; Deoxyribonuclease 2 alpha; Deoxyribonuclease 2; Deoxyribonuclease II alpha; Deoxyribonuclease II; Deoxyribonuclease II lysosomal; Deoxyribonuclease-2-alpha; Deoxyribonuclease2; DeoxyribonucleaseII; DNASE 2; DNASE 2A; DNase II alpha; DNase II lysosomal; DNASE2; DNASE2A; DNaseII; DNL 2; DNL; DNL2; DNS2A_HUMAN; Lysosomal DNase II; R31240 2; R31240_2.

供應(yīng) 商遠(yuǎn)慕生物

研究領(lǐng)域細(xì)胞生物細(xì)胞凋亡細(xì)胞周期蛋白表觀遺傳學(xué)

抗體來源 Rabbit

克隆類型 Polyclonal

交叉反應(yīng) Human, Mouse, Rat, Dog, Pig, Cow, Sheep,

產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 脫氧核糖核酸酶2抗體（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 38kDa

細(xì)胞定位細(xì)胞漿

性狀 Lyophilized or Liquid

濃度 1mg/1ml

免疫原 KLH conjugated synthetic peptide derived from human DNase II

亞型 IgG

純化方法 affinity purified by Protein A

儲(chǔ) 存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

脫氧核糖核酸酶2抗體產(chǎn)品介紹 background:

Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.

Function:
Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.

Subcellular Location:
Lysosome.

Post-translational modifications:
Glycosylated. Mutations that eliminate N-glycosylation sites reduce activity, but enzymatic deglycosylation has no effect.

Similarity:
Belongs to the DNase II family.

Database links:
UniProtKB/Swiss-Prot: O00115.2

important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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脫氧核糖核酸酶2抗體，DNase II應(yīng)用方法

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脫氧核糖核酸酶2抗體，DNase II應(yīng)用方法